All manufacturing services
Scale-Up
Scale-Up & Technology Transfer
Supporting the transition from laboratory or pilot processes toward robust commercial manufacturing.
Use case
Bridging laboratory or pilot knowledge to repeatable commercial batch size with documented risks and operating parameters.
Customer inputs
- Lab/pilot data: yields, profiles, thermal data where available
- Mass and energy balance estimates
- Target commercial batch size and annual volume
- Specification draft and critical quality attributes
- Equipment preferences or constraints
Execution
- Compare route to commercial equipment envelope (volume, MOC, utilities)
- Identify scale-dependent risks: mixing, heat removal, work-up time
- Design pilot or bracketing trial protocol
- Execute trials at qualified scale; sample for full analytics
- Engineering review and update of operating ranges
- Define commercial batch record and readiness checklist
Responsibilities
- Customer: provides process knowledge and approves parameter ranges
- Chemlyst: maps facilities and coordinates trials
- Site: executes trials under site safety and quality systems
Deliverables
- Scale-up risk register and mitigation actions
- Trial report with comparative analytics
- Recommended CPPs and operating window for commercial lots
- Go / no-go recommendation with facility name (under NDA)